Selected Publications

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L. Kooijman, M. Schuster, C. Baumann, S. Jurt, F. Löhr, B. Fürtig, P. Güntert and O. Zerbe: Dynamics of Bacteriorhodopsin in the Dark-Adapted State from Solution NMR, Angew. Chem. Int. Ed., 59 (2020), 20965-72.

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S. U.Vetterli, K. Zerbe, M. Müller, M. Urfer, M. Mondal, S.-Y. Wang, K. Moehle, O. Zerbe, A. Vitale, G. Pessi, L. Eberl, B. Wollscheid and J. A. Robinson: Thanatin Targets the Inter-Membrane Protein Bridge Required for Lipopolysaccharide Transport in Escherichia coli , Science Advances, 4 (2018), eaau2634.

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J. Marino, R. Walser, M. Poms and O. Zerbe: Understanding GPCR Recognition and Folding from NMR Studies of Fragments, RSC Adv., 8 (2018), 9858 – 9870.

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E. Michel, A. Plückthun, O. Zerbe: Peptide-Guided Assembly of Repeat Protein Fragments, Angew. Chem. Int. Ed., 57 (2018), 4576-4579.

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C. Baumann, A. Beil. S. Jurt, M Niederwanger, O. Palacios, M. Capdevila, S. Atrian, R. Dallinger, O. Zerbe: Structural adaptation of a protein to increased metal stress: NMR structure of a marine snail metallothionein with an additional domain, Angew. Chem. Int. Ed., 56 (2017), 4617-4621 (hot paper, highlighted in Science, 356 (2017), 150).

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M. Poms, P. Ansorge, L. Martinez-Gil, S. Jurt, D. Gottstein, K. Caroccia, L. Cohen, P. Güntert, I. Mingarro, F. Naider, O.Zerbe: NMR Investigation of Structures of GPCR Folding Intermediates, J. Biol. Chem., 291 (2016), 27170–2718.

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R. Watson, M. Christen, C. Ewald, F. Bumback, C. Reichen, M. Mihajlovic, E. Schmidt, P. Güntert, A. Plückthun, A. Caflisch, O. Zerbe: Spontaneous Self-Assembly of Engineered Armadillo Repeat Protein Fragments into a Folded Structure, Structure, 22 (2014), 985-995.

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H. Kocherla, J. Marino, X. Shao, J. Graf, C. Zou, O. Zerbe: Biosynthesis and spectroscopic characterization of 2-TM fragments encompassing the sequence of a human GPCR, the Y4 receptor, ChemBioChem, 13 (2012), 818 – 828.:

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R. Walser, J.H. Kleinschmidt and O. Zerbe: A GPCR mini-receptor mimicking the extracellular loops of the human Y1 receptor, ChemBioChem, 12 (2011), 1690-1693.

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Neumoin, L. Cohen, B. Arshava, S. Tantry, J. Becker, O. Zerbe, F. Naider: Structure of a Double Transmembrane Fragment of a G Protein-Coupled Receptor in Micelles, Biophys. J., 96 (2009), 3187-3196.

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J. Mares, S. Kumaran, M. Gobbo, O. Zerbe, Interactions of lipopolysaccharide and polymyxin studied by NMR spectroscopy, J. Biol. Chem., 284 (2009), 11498-11506.

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F. Parmeggiani, R. Pellarin, A. P. Larsen, G. Varadamshetty, O. Zerbe, A. Caflisch, A. Plückthun: Designed Armadillo Repeat Proteins as General Peptide Binding Scaffolds, J. Mol. Biol., 376 (2008),1282-1304.

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A. Neumoin, J.Mares, M. Lerch-Bader, R. Bader and O.Zerbe: Probing the Formation of Stable Tertiary Structure in a Model Miniprotein at Atomic Resolution: Determinants of Stability of a Helical Hairpin, J. Am. Chem. Soc., 129 (2007), 8811-8817.

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Bader, R., Bettio, A., Beck-Sickinger, A., Zerbe, O. (2001): Structure and Dynamics of Micelle-bound Neuropeptide Y: Comparison with unligated NPY and Implications for Receptor Selection, J. Mol. Biol., 305 (2001), 307-329.